A plant alkaloid widely studied for glucose metabolism and AMPK activation.
Berberine HCl is a plant alkaloid with a substantial research base specifically around blood sugar markers and AMPK activation, an enzyme pathway involved in cellular energy regulation.
It's one of the more clinically studied individual ingredients in this category generally, with research often comparing it favorably to some pharmaceutical glucose-management approaches in specific measures.
As with the rest of the formula besides resveratrol, the exact dose used here isn't disclosed in the brand's marketing materials.